In a remarkable first, woman’s advanced breast cancer is eradicated

The majority of women with the most common type of early-stage breast cancer can safely skip chemotherapy after surgery, according to a highly anticipated new report.

A decade-long study revealed that women who take a cancer recurrence gene test and yield results of low or intermediate risk of cancer recurrence - which effects more than 85,000 women a year - can forego chemotherapy altogether, according to CNN. Women 50 or younger can avoid chemo if their scores are lower than 16, said lead author Joseph Sparano, associate director for clinical research at the Albert Einstein Cancer Center in NY.

Avoiding chemotherapy may come as a relief to many women who are diagnosed with breast cancer, as the treatment comes with a number of side effects, including nausea, hair loss and anemia.

For women 50 or younger, chemotherapy is unwarranted for those with an Oncotype score under 16 - about 40 percent of breast cancers in this age group, the researchers said.

Until now, women have faced considerable uncertainty about whether to add chemo to hormone therapy after a diagnosis with hormone-receptor positive, HER-2 negative breast cancer when found at an early stage, before it has spread to the lymph nodes.

Other experts agreed that while these initial results would need to be confirmed in larger clinical trials, they hold promise for a variety of particularly stubborn forms of cancer. Oncotype DX has spurred the trend, and is likely to accelerate it.

Researchers at the National Cancer Institute have put a patient with metastatic breast cancer into complete remission by using a new approach to immunotherapy.

After years of follow up, their results were almost identical with women who received hormone therapy yielding a 93.9 per cent survival rate and those with both therapies a 93.8 per cent survival rate.

An experimental therapy that extracts and multiplies powerful immune-system cells from inside tumors eradicated a patient's breast cancer, a scientific first that could lead to new ways of treating malignancies that have resisted all other efforts.

Chamber of Commerce: Trump trade policies threaten United States jobs
Canadian Prime Minister Justin Trudeau on Friday dubbed trade tariffs imposed by the United States as insulting and unacceptable . And look, the American worker agrees with me.

The rate that women who had also received chemotherapy was more than 84 percent, a statistically insignificant difference.

Results from this study suggest many women with this specific type of tumor do not receive any additional benefit from having chemotherapy in combination with endocrine therapy, compared to endocrine therapy alone.

Lisa Carey, a breast specialist at the University of North Carolina's Lineberger Comprehensive Cancer Center, said she would be very comfortable advising patients to skip chemo if they were like those in the study who did not benefit from it.

Then, five and nine years later, the researchers checked in on how the women were doing.

The findings apply to about 60,000 women a year in the United States, according to Dr Joseph A Sparano of Montefiore Medical Center in NY, the leader of the study.

Perkins hopes she's cured - a word she is nearly afraid to utter - but knows that the cancer "could come back tomorrow". Your odds of being cured are terrific, and you don't need chemotherapy because you don't need it. The money was used to pay for the gene test, which costs more than $4,000 per person.

The test examines the activity of 21 genes of breast cancer tissue and assigns it a score between 0 and 100.

Dr Ring said the trial's reuslts would likely have an immediate impact on United Kingdom practice and represented a significant shake-up in the treatment of early-stage breast cancer. Not only will they be able to dodge the side-effects of chemotherapy but they'll also feel more confident in their decision.

Women can have the tendency to turn towards chemo, even if the results have a relatively small benefit, Albain says.

Related News:



Most liked

Saudi Arabia issues driving licences to women
Ultra-conservatives viewed women driving as immoral and warned they would be subject to sexual harassment if they drove. Others were detained over the years during various efforts by women's rights activists to drive.

Why White House approach to China talks may backfire
All three have plan to retaliate with their own tariffs on USA goods, stoking fears of an escalating conflict. Ross and Liu held a working dinner Saturday ahead of their talks.

Japan may file WTO challenge against USA steel, aluminum tariffs: Aso
Commerce Department numbers show the United States recorded a trade surplus with Canada for each of the past three years. United States and China announced a $50-billion import tariff on each other, only to put the war "on hold" for a while.

Bryson DeChambeau takes one-shot lead as Tiger Woods lurks at Memorial
That left DeChambeau with an eight-foot putt for par and the title but it drifted left and he signed for a one-under 71. Woods was 95 yards out on his third shot and the ball landed just long of the flag before spinning back into the cup.

Steel & Aluminum Tariffs 'Against Agreed International Rules,' Per EU Commissioner Cecilia Malmstrom
That meeting, which will be hosted by Canadian Prime Minister Justin Trudeau, will be Trump's first visit to Canada as president. Commerce Department numbers show, the United States recorded a trade surplus with Canada for each of the past three years.

Serena ‘betrayed’ as Sharapova feud fires up French Open
Sharapova, 30, needed just 59 minutes on Court Philippe Chatrier to emerge victorious 6-2, 6-1 against an out-of-sorts Pliskova . However, Thursday was a tougher proposition for the 36-year-old American, who was playing just her sixth match of this year.

ICC World XI set to face Windies in T20 tie
Prolific Pakistan batsman Shoaib Malik will also feature along with 17-year-old Nepalese spin sensation Sandeep Lamichhane. This was not the first instance the cricketing community is coming together to help those in need.

United States defends latest tariffs on China products
The tariff threat is a "very powerful" negotiating tactic, said Lester Ross, chairman of the American chamber's policy committee. But according to the White House, the date of 15 June is announced which would finalize the question regarding tariffs.

China rejects 'ridiculous' US accusation of South China Sea militarisation
He added that the area was regarded as global waters and many countries wanted to exercise their freedom of navigation. Harry Harris during the change of command on Wednesday.

Roseanne Barr lashes out at "Roseanne" co-stars
Trump wrote that Iger never called him to apologize for "the terrible statements " that have been said about him on ABC . No one is defending her comments. "This is a double standard that the president is speaking about".

Malaysia Says It Will Axe High-Speed Railway to Singapore
The 350-km HSR project with the Singapore portion covering 15 km - was scheduled to be completed by 2026. Mahathir has reopened an investigation into 1MDB that was suppressed during Najib's rule.

Trump wants to bar German luxury cars in US
The Trump administration has opened a trade investigation into whether vehicle imports have damaged the US auto industry. The European Union imposes a 10 percent tariff on cars imported from the U.S.

Kim Kardashian met Donald Trump at White House to discuss prison reform
Kardashian West appeared to preview the visit on her Twitter feed, writing: "Happy Birthday Alice Marie Johnson ". However, if Trump were to grant Alice clemency, it would go against his approach to drugs so far.

LeBron's Finals challenge may be too tall an order, say pundits
The Cavs finished their series Sunday at Boston, so James spent a relaxing Memorial Day Monday with family having a barbecue. This is not their first time being an underdog against the Warriors, and in 2016 the Cavs accomplished the possible.

Zidane departs as the second most successful coach in Real Madrid history
It does not seem as though Zidane was exhausted by the task of managing a high-profile club like Real Madrid . Zidane has won the Champions League four times at Real Madrid - three times as manager and once as a player.